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Updated: Jul 29, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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通过差异甲基化分析确定与焦虑症相关的17种新型表观遗传生物标志物,然后通过基于机器学习的验证

Yoonsung Kwon1,2, Asta Blazyte1,3, Yeonsu Jeon4

  • 1Korean Genomics Center (KOGIC), Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.

Clinical epigenetics
|February 18, 2025
PubMed
概括

研究人员确定了17种与焦虑症相关的新型DNA甲基化生物标志物. 这些表观遗传标记显示出早期诊断和通过血液液体活检进行个性化治疗的前景.

关键词:
焦虑症是一种焦虑障碍.一个表观遗传生物标志物.液体活检液体活检机器学习 机器学习甲基化风险评分 甲基化风险评分

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...