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Updated: May 27, 2025

High-throughput Confocal Imaging of Quantum Dot-Conjugated SARS-CoV-2 Spike Trimers to Track Binding and Endocytosis in HEK293T Cells
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在ACE2的活性部位的结构变化对SARS-CoV-2尖蛋白受体结合域的结合作用

Natalia V Dolgova1, Muhammad Qureshi2, Matthew Latimer2

  • 1Calibr─California Institute for Biomedical Research, Scripps Research, 11119 North Torrey Pines Road, La Jolla, California 92037, United States.

Inorganic chemistry
|February 18, 2025
PubMed
概括

血管酶转化酶2 (ACE2) 的二元形式,包括蛋白酶和子域,是研究SARS-CoV-2尖端蛋白相互作用的更好的模型. 这种二极体ACE2表现出异性,与之前研究的单体形式不同.

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