商业中药局部多草药制剂对性阴道候群病的比较疗效:一个网络的元分析
Lizheng Wu1, Shangwen Jing2, Na Li3
1The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Frontiers in pharmacology
|February 18, 2025
概括
商用中国多草药制剂 (CCPPs) 与常规治疗 (CT) 结合使用,对阴腺候群 (VVC) 有望. 一些CCPP改善了治愈率和减少症状,不显著增加不良影响,但需要更高质量的研究.
科学领域:
- 药理学和治疗学 药理学和治疗学
- 综合医学是一个整体的医学.
- 传染性疾病 传染性疾病
背景情况:
- Vulvovaginal Candidiasis (VVC) 是一种常见的妇科感染.
- 局部商用中国多草药制剂 (CCPP) 经常用于VVC治疗.
- 关于不同CCPP的比较疗效的证据有限.
研究的目的:
- 系统地评估和比较常用的局部CCPPs对VVC的疗效.
- 为涉及CCPPs的临床药物治疗方案提供基于证据的建议.
主要方法:
- 进行了随机对照试验 (RCT) 的系统审查和网络元分析.
- 搜索了主要的中文和英语文献数据库,进行RCT,比较CCPP加常规治疗 (CT) 与单独用于VVC的CT.
- 使用Cochrane偏差风险工具评估研究质量并提取结果数据.
主要成果:
- 包括74个RCT,包括8,151名患者和9个干预措施.
- 富芳·沙吉齐尤 (Fufang Shajiziyou) 假与CT改善了Candida albicans的负转换和复发率.
- 康福凝与CT最好用于缓解,宝福康用于减少白血病,福福康喷雾用于减少不良反应.
结论:
- 将CCPP添加到CT可以增强VVC的治疗效果,而不会显著增加不良反应.
- 包含的文献的整体质量很低.
- 需要更大规模,更高质量的临床研究来证实这些发现.
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