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一个卵巢完整的绝经后HFpEF小鼠模型;绝经不仅仅是雌激素缺乏症

Mei Methawasin1,2, Joshua Strom1, Vito A Marino3

  • 1Department of Cellular and Molecular Medicine and Sarver Molecular Cardiovascular Research Program, University of Arizona, Tucson, Arizona, United States.

American journal of physiology. Heart and circulatory physiology
|February 18, 2025
PubMed
概括

更年期显著增加了女性心力衰竭与保存的喷射率 (HFpEF) 的风险. 使用VCD和2hit方案的新"卵巢完好"小鼠模型成功模仿绝经后的HFpEF,揭示了心肌细胞功能障碍和潜在的雄激素影响.

关键词:
HFpEF HFpEF 的意思是什么腹痛功能障碍 腹痛功能障碍 腹痛功能障碍卵巢-完好无损 绝经期在更年期后的绝经后.

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