遗传和环境因素对横向生长的影响
Sameer Al-Obaidi1, Spyridon N Papageorgiou2, Marianne Saade1
1Department of Orthodontics & Dentofacial Orthopedics, Henry M. Goldman School of Dental Medicine, Boston University, 635 Albany St., Boston, MA 02118, United States.
European journal of orthodontics
|February 18, 2025
概括
遗传和环境因素影响面宽度的发展. 环境因素在15岁时显著影响犬间宽度,而遗传因素在整个童年和青春期对大和下宽度保持强烈影响.
科学领域:
- 矯正牙科 矯正牙科是一種矯正牙科.
- 人类遗传学 人类遗传学
- 面生物学 面生物学
背景情况:
- 了解遗传和环境影响对面发育的相互作用,对于正牙和儿科护理至关重要.
- 双胞胎研究提供了一个强大的模型,用于剖析复杂特征的遗传性和环境贡献.
研究的目的:
- 研究对关键面结构横向生长的遗传和环境影响.
- 在双胞胎的不同发育阶段 (9,12,15岁) 分析这些影响.
主要方法:
- 研究了142名儿童的队列,包括单胞胎和双胞胎双胞胎.
- 后前脑电图被分析为犬间,大,下,鼻和面部宽度.
- 使用结构方程建模来量化变异的遗传和环境成分.
主要成果:
- 大和下的宽度在所有年龄段都表现出强大的遗传影响.
- 狗间和鼻子宽度在15岁时从主要的遗传转变为环境影响.
- 面部宽度显示,随着年龄的增长,遗传影响越来越大,在15岁时达到90%.
结论:
- 面的横向尺寸受到遗传和环境因素的影响,随着时间的推移有不同程度的贡献.
- 环境因素扮演着重要的角色,特别是在犬间宽度,突出潜在的干预领域.
- 这一欧洲血统队列的发现可能对其他族群的概括性有限.
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