与最近有监禁史的与男性发生性关系的男性中比较PrEP使用情况
Gabriel G Edwards1,2, Brandon Moghanian1, Cathy J Reback2,3,4
1Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
AIDS care
|February 18, 2025
概括
内化同性恋恐惧症显著影响与男性发生性关系的男性 (MSM) 中的暴露前预防 (PrEP) 使用,特别是影响性身份差异. 解决内化同性恋恐惧症是改善PrEP在这个人群中吸收的关键.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会和行为科学 社会和行为科学
背景情况:
- 与男性发生性关系的男性 (MSM) 经历过监禁,面临着更高的艾滋病毒传播风险.
- 暴露前预防 (PrEP) 是一种重要的生物医学HIV预防工具.
- 在MSM人口中存在PrEP吸收的差异,受到各种社会人口统计学和心理社会因素的影响.
研究的目的:
- 检查暴露前预防 (PrEP) 使用与最近有监禁史的与男性发生性关系 (MSM) 的男性中艾滋病毒风险增加的因素之间的关联.
- 调查性认同,种族/族裔,监禁史和内部化的同性恋恐惧症在PrEP使用中的作用.
主要方法:
- 基线PrEP使用数据的分析来自洛杉矶县 (2019-2022) 随机对照试验的170名男性识别参与者.
- 使用后勤回归来评估PrEP使用与性认同,社会人口统计学和潜在混因素之间的关联.
- 特别是评估了内化同性恋恐惧症作为调节者的影响.
主要成果:
- 与异性恋/异性恋和双性恋的MSM相比,同性恋/同性恋的MSM使用PrEP的几率更高.
- 黑人/非洲裔美国MSM和累积监禁历史较长的参与者 (<6个月与3年以上) 显示PrEP使用的几率降低.
- 对内部化的同性恋恐惧症进行控制,消除了基于性认同的PrEP使用的显著差异,但不是基于种族/种族或监禁历史.
结论:
- 内部化的同性恋恐惧症是关于性认同的PrEP使用在MSM中差异的重要驱动因素.
- 虽然种族/种族和监禁史与较低的PrEP使用有关,但内化同性恋恐惧症并没有调解这些特定的差异.
- 针对内部化的同性恋恐惧症的有针对性的干预措施可以改善PrEP的吸收率,并降低多样化MSM人群中艾滋病毒传播风险.
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