[非酒精性脂肪肝:新名称,但挑战仍然存在]
Miroslav Vána1,2, Koray Fidan3, Annalisa Berzigotti4,1
1Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Praxis
|February 18, 2025
概括
代谢性肝病,包括新命名的代谢功能障碍相关的脂肪性肝病 (MASLD),越来越常见. 这种转变反映了代谢综合征的日益流行及其对肝脏健康的影响.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢疾病 代谢疾病
- 临床医学 临床医学
背景情况:
- 由于代谢综合征患病率增加,代谢性肝病的患病率正在上升.
- 预计这些疾病将成为未来最常见的肝脏疾病.
- 这篇文章讨论了这些疾病的不断变化的理解和分类.
研究的目的:
- 解释理解代谢性肝病的关键变化.
- 突出名称从非酒精性脂肪性肝病 (NAFLD) 转变为与代谢功能障碍相关的脂肪性肝病 (MASLD).
主要方法:
- 关于新陈代谢性肝病的最近研究的文献综述.
- 对代谢综合征和肝脏疾病的流行病学数据的分析.
- 讨论更新的诊断标准和术语.
主要成果:
- 代谢功能障碍相关的脂肪性肝病 (MASLD) 是新的标准术语.
- 重新命名强调了新陈代谢功能障碍和肝硬化症之间的联系.
- 这一变化旨在改善疾病的识别和管理.
结论:
- 将命名体系改为MASLD意味着在认识到代谢性肝病的影响方面迈出了关键一步.
- 了解MASLD对于应对未来的肝病流行病至关重要.
- 早期识别和治疗代谢功能障碍是预防肝病进展的关键.
更多相关视频
08:41Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
1.0K
08:35A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium
Published on: May 18, 2021
6.2K
相关概念视频
Diseases of the Liver and Gallbladder
414
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
414
Chronic Pancreatitis I: Introduction
64
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
64
Overview of Fatty Acid Metabolism
30.2K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
30.2K
Liver Regeneration
3.2K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
3.2K
Liver Physiology
412
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
412
Chronic Pancreatitis II: Collaborative Care
58
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
58
