对于10项自闭症谱系系数 (AQ10) 使用最佳切割值的重要性
Lucy H Waldren1, Lucy A Livingston2, Rachel A Clutterbuck1
1Department of Psychology, University of Bath.
Psychological assessment
|February 18, 2025
概括
自闭症谱系系数 (AQ10) 查工具经常使用错误的截止分数. 使用最佳得分为6而不是7正确地识别了研究中36.80%的自闭症成年人.
科学领域:
- 心理学 心理学 心理学
- 神经发育障碍 神经发育障碍
- 临床研究 临床研究
背景情况:
- 10项自闭症谱系系数 (AQ10) 是一种广泛使用的成年人自闭症特征查工具.
- 当前的临床实践和研究往往采用7的低于最佳的切断点数,偏离最初开发的6的最佳切断点.
- 很大一部分发表的研究 (超过58%) 错误地报告或使用模两可的AQ10截止值.
研究的目的:
- 调查使用不同切割值 (≥6与≥7) 对自闭症谱系系数 (AQ10) 在分类自闭症特征中的影响.
- 评估国家卫生和护理卓越研究所推的非最佳切断值的准确性和影响.
- 突出使用不正确的切断值对与自闭症相关的研究结果的后果影响.
主要方法:
- 分析了25个已发表的数据集,共计13,692名参与者.
- 对高自闭症特征的分类结果进行比较,使用AQ10截止分数≥6和≥7的分类结果.
- 针对临床自闭症诊断的不同AQ10切线的灵敏度和特异性的评估.
主要成果:
- 应用≥6的最佳AQ10截止值正确识别出高自闭症特征的个体数量增加了36.80%,相比之下,≥7的次优截止值正确识别出高自闭症特征的个体数量增加了36.80%.
- 截止值≥6表明灵敏度和特异性的优越平衡,用于识别临床自闭症诊断的个体.
- 在AQ10截止值的单点差异显著改变了统计学意义和研究中自闭症相关影响的幅度.
结论:
- 广泛使用低于最佳的AQ10截止分数 (≥7) 显著影响研究结果和自闭症个体的识别.
- 迫切需要在临床实践和研究中为准确的自闭症查标准化和实施正确的AQ10截止分数 (≥6).
- 纠正AQ10截止值对于可靠的自闭症研究和确保适当识别自闭症成年人至关重要.
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