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Updated: May 27, 2025

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在状癌中,MLL3/GRHL2复合体调节恶性转变和抗瘤免疫力

Chehyun Nam1, Guowei Huang2,3, Yueyuan Zheng2

  • 1Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, and Norris Comprehensive Cancer Center, University of Southern California , Los Angeles, CA, USA.

The Journal of experimental medicine
|February 18, 2025
PubMed
概括

MLL3基因突变驱动早期上空气消化状细胞癌 (UASCC) 的发展. 这种MLL3/GRHL2通路增强了抗瘤免疫力,并预测了UASCC患者对免疫检查点阻塞 (ICB) 治疗的反应.

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