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扩散性大B细胞淋巴瘤:检查死亡率,发病率和人口统计的不断变化的模式

Silpa Choday¹, Eric Tran², Miguel Gonzalez³

¹Department of Internal Medicine, Creighton University School of Health Science, Phoenix, AZ, USA. silpachoday@creighton.edu.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

|February 18, 2025

概括

扩散性大B细胞淋巴瘤 (DLBCL) 的住院治疗和费用从2016年至2020年增加. 关键的危险因素包括男性性别和65岁,在西班牙裔人口中发病率上升,突出了医疗保健差异.

科学领域:

血液学血液学血液学
在瘤学瘤学.
流行病学流行病学

背景情况:

扩散性大B细胞淋巴瘤 (DLBCL) 是最常见和最具攻击性的非霍奇金淋巴瘤亚型.
DLBCL的特点是显著的异质性,影响患者的治疗结果和治疗策略.

研究的目的:

分析DLBCL住院患者,住院患者死亡率和相关成本的最新趋势.
确定影响DLBCL发病率和结果的人口和临床因素.

主要方法:

使用全国住院患者样本 (NIS) 数据库 (2016-2020) 的回顾性队列研究.
分析包括DLBCL住院,出院和结果,调整了各种人口和医院因素.
使用多变量逻辑回归来评估趋势和风险因素.

主要成果:

由于DLBCL而住院的病例从2016年到2020年增加,诊断时的平均年龄为65岁.
在男性和西班牙裔人口中观察到越来越多的趋势,以及肥胖和高血压等伴随性疾病的增加.
住院患者死亡率出现波动,而医院费用大幅增加;出院模式转向家庭医疗和短期护理.

结论:

白人男性和65岁左右的个人代表了DLBCL的关键人口统计数据.
在西班牙裔人口中DLBCL发病率显著增加,需要进一步调查.
跨种族和人口群体存在DLBCL发病率和生存率的显著差异,需要有针对性的干预措施和公平的医疗保健准入.

关键词:

DLBCL DLBCL 是一个字母.扩散大的B细胞淋巴瘤.住院治疗住院治疗非霍奇金淋巴瘤非霍奇金淋巴瘤趋势趋势趋势

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