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Updated: May 27, 2025

A Treatment Package without Escape Extinction to Address Food Selectivity
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在避免/限制性食物摄入障碍中,对食物线索的神经反应

Jennifer J Thomas1,2,3, Laura Holsen2,3,4, Avery L Van De Water2,4,5

  • 1Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston.

JAMA network open
|February 18, 2025
PubMed
概括

神经成像揭示了与恐惧和感官处理相关的区域中大脑活动的增加,这些区域是患有回避性/限制性食物摄入障碍 (ARFID) 的人. 这项研究确定了ARFID基础上的新型神经生物学电路,为避免食物行为提供了洞察力.

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Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
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