发病率和风险因素的进展的pachychoroid疾病的频谱
Angie Hon Chi Fong1,2, Jinzhi Zhao3,4, Wendy Meihua Wong5
1Hong Kong Eye Hospital, Hong Kong SAR, China.
Retina (Philadelphia, Pa.)
|February 18, 2025
概括
在亚洲队列中,帕奇科罗伊德病谱显示出较低的1年进展率. 高龄,吸烟和RPE不规则与新血管化风险增加有关.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 冠状腺疾病 冠状腺疾病
背景情况:
- 脊髓病谱涵盖了各种疾病,其特点是脊髓变厚.
- 了解进展和风险因素对于管理这些经常是慢性视网膜疾病至关重要.
研究的目的:
- 确定亚洲人口中帕奇科罗伊德病谱表型的1年进展率.
- 为了确定疾病进展和并发症的相关风险因素.
主要方法:
- 对133名参与者进行的前性观察性研究,这些参与者具有亚叶胆道厚度≥300μm.
- 年度评估包括最佳校正视敏度 (BCVA) 和多式成像.
- 诊断分布:不复杂的松性,松性色素表皮病,中央血清性胆色素病,松性新血管病.
主要成果:
- 一年后,平均BCVA或亚叶冠状腺厚度没有显著变化.
- 6.3%的眼睛进展到不同的帕奇科罗伊德诊断; 3.6%的眼睛出现了事件新血管化.
- 新血管化的危险因素包括年龄较大,吸烟以及浅层不规则的视网膜色素表皮的升高.
结论:
- 帕奇科罗伊德病谱表现出相对稳定,在1年内进展率较低.
- 高龄,吸烟和特定的OCT发现 (RPE升高) 与神经血管并发症风险增加有关.
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