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Updated: May 27, 2025

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抑制TSH受体表达的Cyclotriazadisulfonamide作为一个潜在的治疗严重的甲状腺功能障碍症

Christine C Krieger1, Susanne Neumann1, Xiangliang Sui1

  • 1Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Endocrinology
|February 18, 2025
PubMed
概括

一种新型药物VGD040有效地降低了Graves甲状腺功能障碍症中的甲状腺激素受体 (TSHR) 表达. 这种小分子显示出开发这种自身免疫性疾病的安全和有效治疗的潜力.

关键词:
这是CADA的化合物.格雷夫斯病 (Graves disease) 是一种疾病.TSHR的表达方式甲状腺功能过强症 甲状腺功能过强症新生蛋白质降解新生的蛋白质降解.信号是一种信号.

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