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Updated: May 27, 2025

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在英国生物银行中,基因与环境的相互作用背后有不同的解释

Arun Durvasula1, Alkes L Price2

  • 1Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Genetics, Harvard Medical School, Cambridge, MA, USA; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

American journal of human genetics
|February 18, 2025
PubMed
概括

基因与环境的相互作用显著影响复杂的特征和疾病. 本研究开发了检测和量化这些基因环境 (GxE) 效应的方法,揭示了它们对人类变异的重大贡献.

关键词:
复杂的特征是复杂的特征.基因与环境的相互作用统计遗传学统计遗传学

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Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
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