α-synuclein

Han Zhang1, Jieli Zhang2, Xiuna Jing3

  • 1Department of Neurology, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China; Department of Neurology, Nanfang Hospital of Southern Medical University, Guangzhou, China.

概括

寡合性α-synuclein通过激活微质细胞和促进铁亡来触发帕金森病的病理学. STAT3激活是调节这一过程的关键,提供了潜在的治疗点.