对儿科社区获得性肺炎的临床预测模型进行叙述性审查
Chris A Rees1, Stuart Haggie2, Todd A Florin3
1Division of Pediatric Emergency Medicine, Emory University School of Medicine, Atlanta, GA, United States of America; Department of Emergency Medicine, Children's Healthcare of Atlanta, Atlanta, GA, United States of America.
Paediatric respiratory reviews
|February 18, 2025
概括
儿科社区获得性肺炎 (CAP) 的临床预测模型对于识别有风险的儿童至关重要. 虽然LMIC和HIC的模型已经存在,但需要进一步的验证和实施,特别是在LMIC.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 社区获得性肺炎 (CAP) 对全球儿童健康产生重大影响,低收入和中等收入国家 (LMIC) 和高收入国家 (HIC) 之间的发病率和死亡率各不相同.
- 农业政策成果的差异需要开发特定环境的临床预测模型,以确定高风险的儿童.
研究的目的:
- 审查和概述已发表的临床预测模型,用于LMIC和HIC的儿科CAP相关结果.
- 评估目前儿科CAP预测建模的现状,并确定研究和实施方面的差距.
主要方法:
- 对儿科CAP发表的临床预测模型的系统审查.
- 基于预测结果 (治疗失败,不良结果,死亡率,疾病严重程度,需要重大医疗干预) 和地理环境 (LMICs vs. HICs) 的模型分类.
主要成果:
- 在LMICs中,四种模型预测治疗失败,两种模型预测治疗结果不佳,八种模型预测儿科CAP的死亡率. 没有LMIC模型记录了临床实施的影响.
- 在HIC中,三个模型评估疾病严重程度,一个模型预测为儿科CAP进行重大医疗干预的需要.
结论:
- 现有的临床预测模型为高收入国家风险分层提供了基础,但需要更广泛的外部验证和实施.
- 发展,验证和实施有效的儿科CAP临床预测模型,特别是LMICs,以改善患者的治疗结果,是非常必要的.
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