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抗逆流体手术后的长期疗效和生活质量
Philip K Bang1, Naja H Andersen2, Frederik Hvid-Jensen3
1Department of Anesthesiology and Intensive Care, Regional Hospital Viborg, Viborg, Denmark. phiban@rm.dk.
Surgical endoscopy
|February 18, 2025
概括
抗逆流性手术 (ARS) 为胃食道逆流性疾病 (GERD) 症状提供了持久的缓解,尽管一些患者仍然需要长期使用质子抑制剂 (PPI). 在ARS后对潜在的持续PPI使用的认识对于患者管理至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 手术科学 手术科学
- 临床结果研究研究
背景情况:
- 胃食道逆流性疾病 (GERD) 通常用抗逆流性手术 (ARS) 治疗.
- 关于ARS对生活质量和症状控制的长期结果仍然不确定.
- 在ARS后继续使用质子抑制剂 (PPI) 的必要性需要进一步调查.
研究的目的:
- 为了评估ARS的长期疗效.
- 评估ARS对患者生活质量的影响.
- 确定在ARS之后对PPI的长期需求.
主要方法:
- 确定了2012年至2020年期间接受ARS的419名患者队列.
- 为了评估结果,进行了GERD健康相关生活质量 (GERD-HRQL) 问卷调查.
- 质子抑制剂 (PPI) 的使用被追溯分析,使用国家处方数据.
主要成果:
- 包括164名患者,平均随访时间为4.8年.
- 每日胃烧和吐在ARS后显著下降 (从70-90%降至29-32%).
- 手术后5年,47%的患者停止使用PPI,而44%的患者仍然是长期使用者.
结论:
- 抗逆流体手术 (ARS) 在治疗GERD症状方面表现出持续的有效性.
- 很大一部分患者在手术后继续经历每日GERD症状.
- 对于许多ARS患者来说,长期PPI治疗仍然是必要的,这应该在手术前进行沟通.
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