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Pegah HajiAhmadi¹, Hassan Momtaz², Elahe Tajbakhsh¹

¹Department of Microbiology, Shahrekord Branch, Islamic Azad University, PO. Box: 166, Shahrekord, Iran.

Scientific reports

|February 18, 2025

概括

乙组链球菌 (GBS) 是新生儿感染的常见原因. 这项研究发现,孕妇的GBS菌株具有较高的抗生素耐药性,III型和V型是最常见的.

科学领域:

微生物学微生物学
传染性疾病传染性疾病
公共卫生公共卫生

背景情况:

乙组链球菌 (GBS) 殖民孕妇,构成新生儿感染的风险.
了解GBS流行病学,包括血清型和耐药性,对于母亲和婴儿的健康至关重要.

研究的目的:

为了确定GBS囊血清型,病毒性基因和抗生素耐药性模式在伊朗沙赫雷科德的孕妇中的患病率.
评估GBS检测和耐药性基因鉴定分子方法的有效性.

主要方法:

从370名孕妇 (怀孕28至38周) 的阴道抽样被使用PCR和培养方法分析.
进行了囊血型鉴定,病毒性基因检测 (atr,dltS) 和抗生素耐药性概况 (磁盘扩散,多重PCR).

主要成果:

确定了36个GBS分离体 (9.72%). 血清型III (37.83%) 和V (32.43%) 是最常见的.
所有的分离物都携带了ATR和DLTS病毒性基因. 最常见的抗药基因是tetO和erMA (62.16%).
隔离物显示出100%的青素耐药性,但81%的灵敏性对linezolid.

结论:

在孕妇中观察到GBS中抗生素耐药性的高患病率.
分子方法是可靠的GBS识别和检测耐药基因.
需要进一步的研究来确定有效的抗生素,并防止耐药性发展.

关键词:

链球菌的 agalactiaeae 的.抗生素耐药性概况抗生素耐药性概况囊类血清型囊类血清型怀孕妇女的 s.

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