Aβ42PACT/PKR

Vijay Sankar Ramasamy1, Alan Benhur Pravin Nathan2, Moon-Chang Choi3

  • 1Department of Cellular and Molecular Medicine, College of Medicine, Chosun University, Gwangju, 61452, Republic of Korea. vijaysankarr@gmail.com.

Scientific reports
|February 18, 2025
PubMed
概括

阿尔茨海默氏病 (AD) 蛋白质阿米洛伊德-β42 (Aβ42) 通过蛋白激酶R (PKR) 激活触发压力颗粒的形成. 这个过程涉及PACT,与神经退行相关,提供了新的治疗点.

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