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Updated: May 27, 2025

Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients
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Published on: February 7, 2021

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在先前治疗的高级固体癌症中,第二线或随后的免疫检查点抑制剂的最佳早期终点:系统性审查

Jingqiu Li1,2, Xiaoding Zhou1,2, Lei Wu1

  • 1Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.

BMC cancer
|February 18, 2025
PubMed
概括

六个月无进展生存期 (PFS) 可能是治疗高级固体癌症的第二阶段试验中的早期疗效终点,这些癌症使用免疫检查点抑制剂 (ICI) 治疗. 然而,在随机对照试验 (RCT) 中,不建议使用PFS作为总生存期 (OS) 的替代品.

关键词:
晚期固体癌症 晚期固体癌早期疗效终点是早期的疗效终点.免疫检查点抑制剂 免疫检查点抑制剂目标响应 目标响应总体生存率 总体生存率没有进展的生存率.

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