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基于大豆蛋白分离物-麦β-葡萄糖挤出物制备和表征切丁载荷纳米颗粒:相互作用,结构,稳定性和体外释放性质

Jinpeng Li¹, Liang Li²

¹College of Food Science, Northeast Agricultural University, Harbin, 150030, China; College of Food Science and Technology, Bohai University, Jinzhou, 121013, China.

Food research international (Ottawa, Ont.)

|February 19, 2025

概括

豆蛋白分离-大麦β-葡萄糖纳米颗粒有效封装奎尔,增强其稳定性和抗氧化活性. 这些新型载体显示出在营养补充剂和功能性食品中使用的潜力.

科学领域:

食品科学与技术食品科学与技术
材料科学材料科学材料科学
生物化学生物化学

背景情况:

奎尔素是一种强大的抗氧化剂,其稳定性和生物可用性不佳.
开发有效的输送系统对于增强奎尔塞的功能性质至关重要.
豆蛋白分离物 (SPI) 和麦β-葡萄糖 (OG) 是具有封装潜力的生物相容材料.

研究的目的:

开发使用SPI-oatβ-glucan (OG) 结合物的纳米颗粒载体,以提高氨酸的稳定性.
描述素载纳米粒子的封装效率,负载能力和物理性质.
评估这些纳米颗粒对奎尔丁稳定性,抗氧化活性和释放特征的影响.

主要方法:

大豆蛋白分离物 (SPI) 和麦β-葡萄糖 (OG) 通过挤出加工在70-130°C的温度下结合.
奎尔赛丁被封装在SPI-OG挤出纳米颗粒中.
分析了封装效率 (EE),载荷能力 (LC),颗粒大小,奎尔丁结构,稳定性和体外释放.

主要成果:

在90°C和110°C生产的SPI-OG挤出纳米颗粒显示了高封装效率 (80.30%和79.84%) 和负载能力 (50.83%和49.26%).
平均颗粒大小从185.77nm到244.07nm不等,因结合和疏水相互作用,奎尔从晶状转变为无形状态.
纳米颗粒显著改善了奎尔素的储存稳定性 (21天后保持31.89-39.82%) 并在模拟的肠道消化过程中表现出连续释放 (18.99-21.10%的累积释放).

结论:

SPI-OG挤出纳米颗粒作为奎尔素的有效载体,增强其稳定性并延长其生物活性.
开发的纳米颗粒显示出在营养补充剂和功能性食品中的应用潜力.
挤出加工提供了一种可行的方法,用于创建稳定,功能性的氨酸输送系统.

关键词:

挤出纳米颗粒的方法在体外消化过程中消化.麦的β-葡萄糖是一种奎尔丁 (Quercetin) 是一种青素.这是一种大豆蛋白分离物.稳定的稳定性稳定的稳定性结构结构是一个结构.

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