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Updated: May 27, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

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使用化物 - 基因 - 氨基合生成药用化学相关的链接剂

Andrew McGown1, Vesna Vetma2, Damien Crepin1

  • 1Sussex Drug Discovery Centre, School of Life Sciences, University of Sussex, Falmer BN1 9QJ, U.K.

ACS medicinal chemistry letters
|February 19, 2025
PubMed
概括

这项研究表明,用于合成propargylic amines的铜催化A3合. 通过使用奇拉HPLC获得和特征化,使得在药物化学中的应用成为可能,包括用于蛋白质降解的PROTACs.

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