病例报告:由tislelizumab引起的多器官损伤
Man Yuan1,2, Ning Han1,2, Li Shu3
1Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, China.
Frontiers in immunology
|February 19, 2025
概括
免疫检查点抑制剂 (ICI) 可能导致罕见的多器官损伤. 这一案例突出了tislelizumab的累积免疫相关不良事件 (irAEs),导致肺癌患者的严重损伤.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 毒理学 毒理学 毒理学
背景情况:
- 免疫检查点抑制剂 (ICI) 在癌症治疗中至关重要,但可以诱导与免疫相关的不良事件 (irAEs).
- 由irAEs引起的多器官损伤并不常见,但会带来重大的临床挑战.
- 蒂斯莱利祖马布是一种用于治疗各种癌症的ICI,包括肺状细胞癌 (LUSC).
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