从1990年到2019年的全球骨关节炎负担归因于高体重指数
Shiming Yang1, Licheng Zhou1, Wanchen Gong1
1Department of Orthopedics, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China.
Archives of medical science : AMS
|February 19, 2025
概括
与高体重指数 (BMI) 相关的骨关节炎 (OA) 的全球负担从1990年到2019年显著增加. 这种增长在男性中比女性更明显,在南亚和赤道几内亚特别高.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 骨关节炎 (OA) 是全球导致残疾的主要原因.
- 高体重指数 (BMI) 是OA的重要可修改风险因素.
- 了解因高BMI而造成的OA负担的趋势对于公共卫生干预至关重要.
研究的目的:
- 从1990年到2019年,量化归因于高体重指数 (BMI) 的骨关节炎 (OA) 的全球负担.
- 分析与高BMI相关的OA负担的趋势和区域差异.
主要方法:
- 利用了2019年全球疾病负担研究 (GBD) 的数据.
- 劳动残疾调整寿命年 (DALYs) 和年龄标准化的DALY率.
- 应用了比较风险评估框架来估计BMI可归因的OA风险.
主要成果:
- 从1990年到2019年,因高BMI而导致的OA的年龄标准化DALY率每年增加1.45%,从1990年到2019年.
- 这种负担在男性中比在女性中增加的更多.
- 在南亚 (EAPC=3.94) 和赤道几内亚 (EAPC=7.42) 观察到显著增加.
- 归因于高BMI的OA负担在社会人口统计指数 (SDI) 高的地区更高.
结论:
- 由于高BMI而导致的OA的全球负担在1990年至2019年之间显著增加.
- 这种负担不成比例地影响着妇女和老年人.
- 存在地理差异,在高SDI地区和南亚等特定地区的负担更高.
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