一个新的ASAP评分系统和风险表可以预测第二次前列腺活检的结果
Ediz Caner1, Akan Serkan1, Kaya Neslihan2
1Department of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
Archives of medical science : AMS
|February 19, 2025
概括
一个新的评分系统 (ASS-RT) 可以帮助决定进行第二次前列腺活检以检测非典型小瘤扩散 (ASAP). 7或更高的分数表明需要重新活检,可能会避免低风险患者不必要的手术.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 在前列腺活检上的非典型小瘤扩散 (ASAP) 需要谨慎管理.
- 确定ASAP重复前列腺活检的必要性具有临床意义.
研究的目的:
- 评估诊断为ASAP的患者进行第二次前列腺活检的必要性.
- 开发和验证一个评分系统和风险表 (ASS-RT) 以指导重复前列腺活检决策.
主要方法:
- 对2845个通过直肠超声波导向的前列腺活检进行了回顾性审查.
- 对128名ASAP患者的分析,包括PSA水平和ASS-RT得分.
- 接收器操作特征 (ROC) 曲线分析,以确定ASS-RT的最佳切断线.
主要成果:
- ASAP评分系统和风险表 (ASS-RT) 显示出显著的诊断性能 (AUC = 0.804,p=0.001).
- 一个ASS-RT得分≥7显示了60.8%的灵敏度和80.5%的特异性检测前列腺癌.
- 较高的ASS-RT得分与前列腺癌的存在显著相关 (p=0.001).
结论:
- ASS-RT得分可以帮助分层ASAP患者,需要第二次前列腺活检.
- 推的ASS-RT切断点数≥7表明进行重复活检.
- 这种评分系统可能有助于减少选择低风险患者不必要的活检.
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