在艾滋病毒感染者中,大麻使用和自我报告的烦人的症状
Aleksandra Wrona1,2, Amy C Justice1,2, Janet P Tate1,2
1VA Connecticut Healthcare Systems.
Cannabis (Albuquerque, N.M.)
|February 19, 2025
概括
大麻使用在艾滋病毒 (PWH) 感染者中很常见,并且与更烦人的身体和心理健康症状有关,包括记忆,抑郁和焦虑等问题. 需要进一步的研究来了解这些有关协会.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 艾滋病毒/艾滋病研究研究
背景情况:
- 大麻使用在艾滋病毒感染者 (PWH) 中普遍存在.
- 有限的研究存在于与PWH中大麻使用相关的健康结果.
- 了解这些关联对于管理PWH健康至关重要.
研究的目的:
- 评估大麻使用与PWH中烦人的身体和精神健康症状之间的关联.
- 为了比较自我报告的大麻使用与生物标志物确认的使用.
- 在这个人群中识别与大麻消费相关的特定症状.
主要方法:
- 跨队列研究 (MASH) 涉及来自多个艾滋病毒队列 (SHCS,KPNC,VACS-HIV) 的PWH.
- 利用艾滋病毒症状指数进行自我报告的症状和指甲剪切用于大麻生物标志物分析.
- 调整为人口因素的物流回归模型被用于评估关联.
主要成果:
- 27%的PWH报告使用大麻或通过生物标志物检测出阳性.
- 在20个症状中,有19个症状在大麻使用者中更为普遍,在麻烦的水平上.
- 在大麻使用和令人不安的记忆,抑郁,焦虑和恶心症状之间发现了显著的关联.
结论:
- 大麻使用在PWH中很常见,并与许多令人烦的症状有关.
- 虽然可能用于食欲或恶心,但与抑郁症,焦虑和记忆问题的关联需要进一步调查.
- 这些发现强调了在PWH管理中需要仔细考虑大麻使用的必要性.
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