在怀疑长期COVID的儿童中,临床特征和血清阳性之间的关联较差-一项单中心研究
S Olsson-Åkefeldt1,2, J Luthander1,2, L Anmyr3,4
1Department of Paediatric Infectious Diseases, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Acta paediatrica (Oslo, Norway : 1992)
|February 19, 2025
概括
怀疑长期COVID的儿童,无论SARS-CoV-2抗体状况如何,都经历了许多症状和健康状况不佳. 多学科护理对于解决儿科长期COVID的广泛影响至关重要.
科学领域:
- 儿科健康 儿科健康
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 儿童长期COVID presents一个复杂的临床挑战.
- 了解儿科长期COVID的特征对于有效管理至关重要.
- 在儿童长期COVID症状中SARS-CoV-2感染的作用需要进一步调查.
研究的目的:
- 在专家长期COVID诊所中,比较具有和没有SARS-CoV-2抗体的儿童的临床表现和特征.
- 为了确定儿童长期COVID患者的常见症状和功能障碍.
- 评估血清状况对儿科长期COVID的症状学的影响.
主要方法:
- 在一个多学科计划中对113名儿童和青少年进行横截面研究.
- 数据收集包括标准化采访,临床和流行病学评估.
- 进行了SARS-CoV-2尖端抗体测量.
主要成果:
- 52%的儿童与SARS-CoV-2感染有血清学联系.
- 疲劳,炼后的不适,头,头痛和注意力集中障碍是常见的症状.
- 血清阴性儿童报告了更多的个体症状和更高的缺学率和活动中断.
结论:
- 儿科长期COVID患者表现出多样化的症状和自我报告的健康状况不佳,无论SARS-CoV-2抗体状态如何.
- 症状呈现表明多因素的原因超出了直接的病毒感染.
- 多学科评估对于管理儿科长期COVID的广泛影响至关重要.
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