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Updated: May 27, 2025

Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
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在未来的新出现的呼吸道感染流行病期间,用于疫苗疗效试验的数学建模

Soyoung Kim1, Sun Hee Park2,3, Sunhwa Choi1

  • 1Innovation Center for Industrial Mathematics, National Institute for Mathematical Sciences, Seongnam-si, Gyeonggi-do, Republic of Korea.

Human vaccines & immunotherapeutics
|February 19, 2025
PubMed
概括

针对新兴流行病的疫苗随机对照试验 (RCT) 的时间影响所需的样本大小,而不是疫苗疗效 (VE). 早期试验启动和扩展招募可以减少样本大小的需求,而不会影响VE.

关键词:
新出现的呼吸道传染病.流行病 流行病 流行病数学建模的数学建模权力,权力,权力,权力.随机对照试验是随机对照试验.样本的大小 样本大小疫苗的有效性 疫苗的有效性

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