在巴西中西部住院期间与结核病死亡相关的因素
Ademar Rodrigues de Oliveira Junior1, Cláudia Elizabeth Volpe-Chaves2,3, Mara Luci Gonçalves Galiz Lacerda2
1Hospital Universitário Maria Aparecida Pedrossian, Campo Grande, Mato Grosso do Sul, Brazil.
Revista do Instituto de Medicina Tropical de Sao Paulo
|February 19, 2025
概括
结核病 (TB) 显著影响住院患者,在巴西观察到33%的死亡率. 死亡的主要风险因素包括晚年,中枢神经系统结核病和重症监护室的入院.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 结核病 (TB) 仍然是全球主要的死亡原因,特别影响艾滋病毒感染者.
- 由于COVID-19的流行,结核病的发病率加剧了,特别是在像巴西这样的高负担国家.
- 有限的数据存在于住院结核病患者的死亡率模式.
研究的目的:
- 分析住院结核病患者的临床和流行病学特征.
- 为了确定与这一群体的死亡率相关的重大风险因素.
- 为第三级医院环境中结核病管理挑战提供见解.
主要方法:
- 在巴西中西部2017-2019年期间对154名住院结核病患者进行了回顾性研究.
- 评估患者的人口统计,并发症和临床管理细节.
- 统计分析以确定与住院死亡率相关的因素.
主要成果:
- 这项研究包括154名患者 (74.68%是男性,平均年龄为48岁).
- 伴随性疾病包括糖尿病和慢性肺炎;2857%需要接受ICU治疗.
- 死亡率为33.12%,主要死因是败血症和呼吸衰竭.
结论:
- 晚年,中枢神经系统结核病,意识减弱,ICU入院,机械呼吸和血管活性药物使用与较高的死亡率有关.
- 住院患者的高死亡率凸显了结核病的严重程度和临床管理的困难.
- 迫切需要实施战略,以减少与结核病相关的死亡率.
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