修改过的阿特金斯饮食对的婴儿和儿童生长的影响
Joshua Chang1, Stephanie Schimpf1, Chalongchai Phitsanuwong1
1Section of Pediatric Neurology, Department of Pediatrics, The University of Chicago, Chicago, Illinois, USA.
Epileptic disorders : international epilepsy journal with videotape
|February 19, 2025
概括
经过修改的阿特金斯饮食 (MAD) 在12个月内没有显著影响儿童的线性生长. 然而,较高的代谢性酸性酶水平与生长减缓有关,突出显示需要仔细监测.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 营养科学 营养科学
背景情况:
- 性饮食 (KD) 是一种公认的治疗方法.
- 有关KD潜在的线性生长限制存在担忧,特别是在儿科患者群体.
- 有限的数据存在于修改的阿特金斯饮食 (MAD) 和其对生长的影响.
研究的目的:
- 评估修改的阿特金斯饮食 (MAD) 对儿童和婴儿生长指标的影响,特别是线性生长.
- 在MAD开始后,每隔1,6个月和12个月评估成长.
主要方法:
- 儿童患者在专门诊所接受MAD的回顾性分析.
- 数据收集包括基线的身高,体重和BMI Z-scores以及1,6和12个月的随访.
- 对Z分数进行比较,以评估增长参数的变化.
主要成果:
- 从基线到MAD启动6或12个月后,没有观察到身高Z分数的统计学上显著差异.
- 按年龄组分层的分析,包括婴儿和3岁以下的儿童,对身高Z分数没有显著影响.
- 较高的代谢酸性化水平 (血清二碳酸盐<20mEq/L) 与对线性生长的显著负面影响有关,与化水平不同.
结论:
- 修改后的阿特金斯饮食 (MAD) 在儿童患者的线性生长方面似乎是安全的,长达12个月.
- 代谢性酸是影响MAD生长的潜在混因素,需要监测.
- 进一步的研究可能会探索长期生长结果和代谢参数的最佳管理.
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