紧急诊所医生 布普伦诺芬 开始,后续处方和持续处方
Annette M Dekker1, David L Schriger1,2, Andrew A Herring3,4
1Department of Emergency Medicine, David Geffen School of Medicine, University of California, Los Angeles.
JAMA
|February 19, 2025
概括
在加利福尼亚州,从2017年到2022年,急诊医生越来越多地为阿片类药物使用障碍 (OUD) 开处方. 在ED开始服用布普伦诺芬的患者中,大约9分之一的患者在一年内获得连续处方.
科学领域:
- 紧急医疗
- 药物成
- 公共卫生
背景情况:
- 在美国,阿片类药物使用障碍 (OUD) 和相关死亡率仍然是严重的公共卫生问题.
- 布普伦诺芬治疗有效降低了与OUD相关的发病率和死亡率.
- 国家倡议旨在扩大急诊室 (ED) 的布普伦诺芬启动范围,以达到服务不足的人群.
研究的目的:
- 分析加利福尼亚州紧急诊所医生开始使用布普伦诺芬的趋势.
- 检查ED启动布伦诺芬后的随后处方模式和护理连续性.
- 评估随着时间的推移,急诊医生处方布普伦诺芬的变化.
主要方法:
- 使用加利福尼亚控制物质利用审查和评估系统 (CURES) 数据库的回顾性观察研究.
- 分析2017年1月1日至2022年12月31日的布普伦诺芬处方情况.
- 纳入标准:加利福尼亚州邮政编码的18-79岁患者,他们填写了布普伦诺芬处方.
主要成果:
- 紧急诊所医生的布普伦诺芬处方参与率从2017年的2%上升到2022年的16%.
- 在研究期间,急诊医生的布普伦诺芬开服处方从0. 1%增加到5%.
- 在ED开始后40天内接收第二份处方的患者的连续处方率为2. 8; 9. 1% 患者在一年内接收连续处方.
结论:
- 加利福尼亚州的急诊医生在2017年至2022年间显著增加了对OUD的布普伦诺芬处方.
- 在ED开始服用布普伦诺芬的患者中,很大一部分患者随后继续接受治疗.
- 这些发现支持急诊室在扩大OUD治疗的作用.
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