通过集体迁移进行非遗传适应.
Lam Vo1,2, Fotios Avgidis1,2,3, Henry H Mattingly4
1Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511.
概括
细菌群体通过集体迁移和偏好高性能游泳细胞,快速适应新环境. 这种动态的适应发生在没有遗传变化的情况下,展示了灵活的生存策略.
科学领域:
- 微生物学 微生物学
- 进化生物学 进化生物学
- 系统生物学 系统生物学
背景情况:
- 细胞群需要适应环境变化才能生存.
- 适应可以通过基因调节或基因突变发生.
- 细菌群体表现出多样化的表型,包括不同的游泳行为.
研究的目的:
- 研究迁徙细菌种群如何调节它们的表型分布以适应不同的环境.
- 了解迁移细菌群体快速表型适应的基础机制.
- 为了确定适应是否涉及遗传变化或表型选择.
主要方法:
- 产生的同源性大肠杆菌菌种群具有不同的游泳行为.
- 在液态和多孔环境中迁移期间观察到的表型分布.
- 在化疗过程中测量化学受体丰度分布.
主要成果:
- 迁徙群体在不同的环境中富含高性能游泳表型.
- 适应发生迅速,没有突变或基因调节,并在停止迁移后逆转.
- 适应同时影响了多个与化学反应相关的特征.
- 细胞生长和集体迁移之间的平衡推动了适应.
结论:
- 集体迁移使细菌群体中的表型组成能够快速灵活地适应.
- 迁移期间的表型选择是适应环境条件的关键机制.
- 这种机制允许具有连续,多维表型的种群在没有遗传变化的情况下适应.
相关概念视频
Migration
7.9K
Migration is long-range, seasonal movement from one region or habitat to another. This common strategy, carried out by many different organisms around the world, is an adaptive response that typically corresponds to changes in an organism’s environment, like resource availability or climate. Migrations can involve huge groups of thousands of animals as well as single individuals traveling alone and can range from thousands of kilometers to just a few hundred meters.
7.9K
Natural Selection and Adaptation
158
Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations,...
Beyond physical adaptations,...
158
Gene Flow
34.6K
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
34.6K
Genetic Drift
39.2K
Natural selection—probably the most well-known evolutionary mechanism—increases the prevalence of traits that enhance survival and reproduction. However, evolution does not merely propagate favorable traits, nor does it always benefit populations.
39.2K
Cell Migration
4.7K
Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and regeneration, immune response, and metastasis. Cells migrate in response to chemical or mechanical signals generated by specific organs or tissues. The overall mechanism includes three steps - polarization, protrusion, and release. Polarization involves the formation of a distinct cell front and rear, which determines the direction of movement.
4.7K
What is Natural Selection?
114.3K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
114.3K


