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鼻上皮质细胞中异常的纯素代谢通过调节Th17/Treg细胞影响过敏性鼻炎

Ting Xu1,2,3, Shitong Xia2,3, Xingjie Zhang2,3

  • 1Department of Otolaryngology-Head and Neck Surgery, Wuxi Clinical Medical College, Nantong University, Wuxi, People's Republic of China.

American journal of physiology. Cell physiology
|February 19, 2025
PubMed
概括

这项研究表明,过敏性鼻炎 (AR) 儿童的高丁含量会破坏 purin代谢,增加 Th17/Treg 失衡和 AR 进展. 通过像DPCPX这样的Adora1抑制剂准这一途径,为患有AR的幼儿提供了一个新的治疗策略.

关键词:
爱慕一个人.在Th17细胞中.在Treg细胞中.过敏性鼻炎 过敏性鼻炎亚丁 (Xanthine) 是一种亚素.

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