在新生儿重症监护室的多药耐药生物和细菌大麦菌殖民:一个队列研究
Marie-Alix Camphuis1, Marine Vincent1, Olivier Dauwalder2
1From the Department of Neonatology.
The Pediatric infectious disease journal
|February 19, 2025
概括
多种耐药生物 (MDROs) 和细菌常见于住院新生儿的便中. 监测运输时间可以优化隔离协议,并指导抗生素治疗.
科学领域:
- 新生儿微生物学 新生儿微生物学
- 传染病监测 传染病监测 传染病监测 传染病监测
- 公共卫生 公共卫生
背景情况:
- 新生儿微生物群运输监测对于预防感染至关重要.
- 专注于住院婴儿的多药耐药生物 (MDROs) 和大麦芽菌.
- 评估运输时间和感染风险至关重要.
研究的目的:
- 评估住院新生儿便中MDROs和B. cereus的流行情况.
- 为了确定这些生物体的运输时间.
- 评估携带MDRO或B. cereus的新生儿感染的风险.
主要方法:
- 基于人口的回顾性研究.
- 从出生到出院的每周便培养的分析 (2018年1月 - 2020年9月).
- 将所有住院新生儿纳入一个单一的三级单位;收集感染数据.
主要成果:
- 其中包括1409名婴儿;15.6%携带MDRO和/或B. cereus.
- MDROs的发生频率比B. cereus (20.5%) 高 (74.1%). 肠杆菌cloacae是最常见的MDRO.
- 没有观察到B. cereus感染;7.4%的患有MDROs的婴儿患有感染.
结论:
- 在住院新生儿的便中经常检测到MDRO和B. cereus.
- 识别运输及其持续时间有助于调整隔离协议.
- 抗生素治疗的指导可以通过运输数据来获取信息.
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