患有缺血性中风的年轻成年人中血管风险因素负担的时间趋势:佛罗里达州中风登记处
Aaron Shoskes1,2, Lili Zhou2, Hao Ying2
1Department of Neurology, University of Utah, Salt Lake City.
Neurology
|February 19, 2025
概括
血管风险因素在年轻的缺血性中风患者中越来越普遍,多发病率在十年内显著增加. 这一趋势不成比例地影响非西班牙裔黑人和男性患者,强调了年轻人群中早期预防策略的必要性.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 年轻成年人 (18-55岁) 的缺血性中风 (IS) 传统上与老年人群的原因不同.
- 然而,年轻成年人血管风险因素 (VRF) 的上升可能导致类似的IS风险概况.
- 本研究研究了年轻IS患者的VRF患病率和趋势.
研究的目的:
- 在年轻的缺血性中风 (IS) 患者中调查血管风险因素 (VRF) 的患病率.
- 在这个人口群体中分析VRF负担的时间趋势.
- 在年轻的IS人群中确定VRF患病率和多发病率的差异.
主要方法:
- 从Get With the Guidelines-中风医院收集未来的数据 (佛罗里达州中风注册,2014-2022年).
- 包括被诊断患有IS的18-55岁患者,分为18-35岁和36-55岁的年龄组.
- VRF包括高血压,失脂症,肥胖,吸烟,心房动,冠状动脉疾病,心力衰竭,糖尿病和睡眠呼吸暂停;多发病率定义为≥3个VRF.
主要成果:
- 包括36488名IS患者;9.2%的年龄在18-35岁之间,90.8%的年龄在36-55岁之间.
- 非西班牙裔黑人患者在两个年龄组中的多发病率高于白人或西班牙裔患者 (p < 0.001).
- 从2014年到2022年,多发病率在两个年龄组显著增加 (10.9%到16.4%在18-35岁,p=0.002;34.6%到41.9%在36-55岁,p<0.001).
结论:
- 年轻的缺血性中风患者越来越多地出现传统的血管风险因素.
- 高多发症不成比例地影响非西班牙裔黑人和男性患者,并且正在上升.
- 针对年轻人群中的VRF的紧急初级预防工作对于打击日益增长的中风发病率至关重要.
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