黄素对化物诱导的骨损伤的保护作用:对肉片病理学和骨生物力学的影响
Qi-Yong Zuo1, Hai-Qiang Meng1, Mohammad Mehdi Ommati1
1Henan Key Laboratory of Environmental and Animal Product Safety, Henan University of Science and Technology, Kaiyuan Avenue 263, Luoyang, Henan 471000, PR China.
Poultry science
|February 19, 2025
概括
饮食中的化物 (F) 负面影响子的行为,骨健康和抗氧化剂水平. 黄素 (Cur) 补充剂可以减轻这些不良影响,改善骨生物力学和纠正异常行为.
科学领域:
- 动物科学动物科学
- 毒理学 毒理学 毒理学
- 营养生物化学 营养生物化学
背景情况:
- 化物 (F) 是一种常见的环境污染物,可能对动物健康产生不利影响.
- 黄素 (Cur) 是一种天然化合物,具有抗氧化和抗炎性质.
- 了解F和Cur在家禽中的相互作用对于优化动物福利和生产率至关重要.
研究的目的:
- 为了研究化物 (F) 和黄素 (Cur) 对带生物力学,组织病理学和幼行为的影响.
- 评估黄素补充剂对化物诱导毒性的保护作用.
主要方法:
- 希林布朗小被分配给8个实验组,饮食中化物 (0-1200毫克/公斤) 和黄素 (0-200毫克/公斤) 的含量各不相同.
- 评估了骨的生物力学特性,组织病理学和行为模式.
- 分析了抗氧化能力和骨原蛋白纤维积累.
主要成果:
- 高水平 (1200毫克/公斤) 诱导了异常行为,降低了骨生物力学强度 (弹性模量,最大应力,性) 和增加了性.
- 化物暴露导致叶皮层变厚,椎骨扩大,过度的原纤维积累,抗氧化能力下降.
- 黄素补充剂 (200 mg/kg) 缓解了异常行为,减少了骨病理变化,并恢复了抗氧化能力.
结论:
- 化物暴露会对子的行为,骨完整性和抗氧化剂状况产生负面影响.
- 黄素补充剂有效地减轻了化物诱导的氧化应激和皮骨的形病理损伤.
- 黄素有可能减轻化物毒性,并改善家禽的动物福利.
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