相关实验视频

Updated: May 27, 2025

Ubiquitous and Tissue-specific RNA Targeting in Drosophila Melanogaster using CRISPR/CasRx
06:37

Ubiquitous and Tissue-specific RNA Targeting in Drosophila Melanogaster using CRISPR/CasRx

Published on: February 5, 2021

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可重新编程的RNA向CRISPR系统是从RNA毒素-抗毒素进化而来的

Shai Zilberzwige-Tal1, Han Altae-Tran2, Soumya Kannan1

  • 1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell
|February 19, 2025
PubMed
概括

研究人员追踪了针对RNA的CRISPR-Cas13系统的演变,发现它们可能起源于流产性感染 (AbiF) 毒素-抗毒素系统. 这项研究揭示了促使进化转型的关键结构变化.

关键词:
关于CRISPR的研究其他国家通过RNA引导的机制细菌免疫力毒素-抗毒素系统

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