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[在胃癌中使用PD-1抑制剂的新辅助和转化疗法的进展]

Y F Tang¹, B Q Zhou¹, S M Dai²

¹The First School of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China Department of General Surgery, the 940th Hospital, Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, China.

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

|February 19, 2025

概括

编程死亡受体-1 (PD-1) 抑制剂在晚期胃癌治疗方面表现有前途. 本综述探讨了它们在新辅助和转化疗法中的使用,以改善患者的治疗结果.

科学领域:

在瘤学瘤学.
免疫治疗是一种免疫疗法.
胃肠病学胃肠病学

背景情况:

胃癌 (GC) 是中国普遍存在的消化系统恶性瘤.
免疫疗法,特别是编程死亡受体-1 (PD-1) 抑制剂,正在推进高级GC的治疗选择.
最近的临床研究强调了免疫治疗在新辅助和转化疗法中对高级GC的疗效.

研究的目的:

审查当前关于胃癌治疗中PD-1抑制剂的研究进展.
专注于PD-1抑制剂在高级GC的新辅助和转化疗法的应用.

主要方法:

最近国内和国际临床研究的文献综述.
对GC治疗中PD-1抑制剂的研究进展的分析.

主要成果:

免疫疗法,包括PD-1抑制剂,在高级GC的新辅助和转换疗法设置中显示出更好的疗效.
越来越多的证据支持PD-1抑制剂在改善晚期胃癌患者治疗结果中的作用.

结论:

基于PD-1抑制剂的组合疗法在治疗晚期胃癌方面取得了重大进展.
对用于新辅助和转化疗法的PD-1抑制剂的进一步研究是有必要的,以优化胃癌的治疗策略.

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