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Updated: May 27, 2025

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质谱法和数学PK/PD模型用于决策树引导的共价药物开发

Md Amin Hossain1,2,3, Rutali R Brahme1,2, Brandon C Miller1

  • 1Department of Chemistry and Chemical Biology, Northeastern University;Boston, Massachusetts, 02115, USA.

Nature communications
|February 19, 2025
PubMed
概括

这项研究引入了对共价药物发现的新工作流程,改进了成功识别和PK/PD建模. 它解决了对共价药物的现有方法的局限性,提高了药物开发效率.

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