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Updated: Jul 19, 2026

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从健康的韩国受试者获得的Streptococcus salivarius菌株的完整基因组和转录组数据集

Eun-Young Jang^1,2, Ji-Hoi Moon³, Jae-Hyung Lee⁴

¹Department of Oral Microbiology, College of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea.

Scientific data

|February 19, 2025

概括

这项研究介绍了来自韩国的12种Streptococcus salivarius菌株的基因组和转录组数据. 这些有益的口腔细菌与Fusobacterium nucleatum具有独特的相互作用,有助于研究口腔微生物群健康.

科学领域:

微生物学微生物学
基因组学就是基因组学.
口腔健康口腔健康

背景情况:

口腔微生物群对健康至关重要,Streptococcus salivarius因其益生菌性质而闻名.
对S. salivarius菌株的研究在很大程度上排除了亚洲人群,特别是韩国人.

研究的目的:

提供来自韩国健康个体的S. salivarius菌株的基因组序列和转录形状.
描述菌株变异及其与诸如Fusobacterium nucleatum等病原体的相互作用.

主要方法:

使用PacBio SMRTbell技术进行基因组测序.
转录形状分析用于分析基因表达模式.

主要成果:

为12个S. salivarius菌株生成了完整的基因组序列和转录基因数据.
每个菌株都表现出与Fusobacterium nucleatum的独特相互作用模式.

结论:

这一数据集为韩国S. salivarius菌株及其多样化的相互作用提供了宝贵的见解.
该资源支持对有益的口腔细菌及其在健康和疾病中的作用的研究.

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