在患有和没有偏头痛的妇女中,中风病因和白质负担
Anne E Wilms1, Nelleke van der Weerd1,2, Thijs W van Harten3,4
1Department of Neurology, Leiden University Medical Center, PO Box 9600, Leiden, 2300RC, The Netherlands.
The journal of headache and pain
|February 19, 2025
概括
患有偏头痛和中风的妇女有更多未确定的中风原因,而在没有偏头痛的中风患者中,吸烟更为常见. 偏头痛并没有增加中风妇女的白质超强度.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 医学研究 医学研究
背景情况:
- 偏头痛,特别是与光环 (MA) 相关的偏头痛,增加了女性患白质过强度 (WMH) 和缺血性中风的风险.
- 了解中风病因和偏头痛妇女的WMH负担对于风险评估和管理至关重要.
研究的目的:
- 为了比较患有偏头痛和没有偏头痛的女性之间的中风病因.
- 评估偏头痛对患有中风的女性白质强度过高 (WMH) 体积的影响.
主要方法:
- 包括40-60岁的女性,有史以来缺血性中风,偏头痛或两者兼而有之.
- 使用TOAST标准对中风病因进行了分类,并通过3D-FLAIR成像测量了WMH体积.
- 用人回归分析,根据年龄,BMI,高血压和吸烟状况进行调整.
主要成果:
- 与单独的中风 (27%) 相比,中风和偏头痛 (49%) 的女性中不确定来源的中风更频繁.
- 患有中风和偏头痛的女性表现出比单独患有MA (0.42mL) 的女性更高的周周结膜WMH体积 (0.55mL).
- 偏头痛没有显著影响中风妇女的整体WMH体积.
结论:
- 患有中风和偏头痛的女性更有可能患有未确定的中风原因.
- 吸烟是患有中风但没有偏头痛的女性更普遍的危险因素.
- 偏头痛本身似乎不会加剧曾经中风的女性的WMH体积.
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