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在创伤患者中,输血量与24小时死亡率相关
Mary L Wallace1, Ryan A Kingrey1, Julie A Rizzo2,3
1University of Kansas School of Medicine, Kansas City, Kansas, USA.
Transfusion
|February 20, 2025
概括
这项研究发现,输血的红细胞 (RBC) 和低标位组O全血 (LTOWB) 单位的数量,以及血液制品的总体数量,无法预测创伤患者的24小时死亡率. 需要更多的研究来了解输血的影响.
科学领域:
- 创伤护理的护理人员.
- 输血药物 输血药物 输血药物
- 关键护理研究研究 关键护理研究
背景情况:
- 有限的数据存在于输血量和创伤死亡率之间的相关性.
- 这项研究调查了红细胞和LTOWB单位以及血液产品总体量与创伤患者24小时死亡率之间的关联.
研究的目的:
- 确定输血红细胞 (RBC),低标位组O全血 (LTOWB) 和血液产品总体量与创伤患者24小时死亡率之间的关联.
主要方法:
- 从2020-2022年使用的创伤质量改善计划 (TQIP) 数据集.
- 包括接受血液制品的15岁以上的患者.
- 雇佣接收者运行特征 (ROC) 分析,以评估输血量与24小时死亡率之间的预测关联.
主要成果:
- 对144,379次遭遇的分析显示,24小时内有22,467人死亡.
- 56个RBC/LTOWB单位 (AUROC 0.673) 与90%的24小时死亡率有关.
- 输血产品的36,000毫升与90%的24小时死亡概率有关 (AUROC 0.662).
结论:
- 无论是RBC/LTOWB单位的总数还是血液制品的总量都没有显著预测平民创伤人口的24小时死亡率.
- 输血量与死亡风险之间的预测相关性很差.
- 对影响创伤死亡率输血后因素的进一步调查是有必要的.
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