直接入院患者和转移患者的大型缺血性中风的内血管治疗:二次分析
Man Li1,2, Lina Zheng1,2, Ximing Nie1,2
1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
概括
内血管治疗 (EVT) 对急性大血管封闭 (LVO) 中风患者有益,无论他们是否在医院之间转移. 这项研究发现,基于医院间转移状态的EVT有效性没有差异,证实了其对所有符合条件的LVO患者的价值.
科学领域:
- 神经学 神经学
- 干预心脏病学 干预心脏病学
- 脑卒中医学 脑卒中医学
背景情况:
- 内血管疗法 (EVT) 是为急性大血管封闭 (LVO) 中风与大心脏病发作而建立的.
- 医院间转移状态对这些患者的EVT疗效的影响尚不清楚.
研究的目的:
- 评估EVT在急性前部循环LVO患者的大型心脏病发作中的有效性.
- 确定医院间转移状态是否会影响EVT的结果.
主要方法:
- 参与了455名患者的ANGEL-ASPECT试验的二次分析.
- 患有急性前部循环LVO和大心脏病发作 (ASPECTS 3-5或心脏病核心70-100毫升) 的患者被随机分配到EVT加医疗管理 (MM) 或单独MM.
- 患者被分为直接入院或医院间转移子组.
主要成果:
- 转移子组经历了更长的开始到达时间 (379分钟对279分钟).
- 在90天的功能结果 (修改的兰金表) 中,EVT在直接 (gOR=1.67) 和转移 (gOR=1.60) 组中都显示出显著的好处.
- 转移状态和治疗效果之间没有发现显著的相互作用 (p=0.706).
结论:
- 在急性前部循环LVO患者的大型心脏病发作中,EVT的治疗益处是一致的.
- 在直接入院的患者和从其他设施转移的患者之间,EVT的疗效没有显著差异.
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