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Updated: May 27, 2025

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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在BTK抑制剂治疗后,抵抗机制和慢性淋巴细胞白血病的方法

Christine Gruessner1, Adrian Wiestner1, Clare Sun1

  • 1Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

Leukemia & lymphoma
|February 20, 2025
PubMed
概括

在白血病中对布鲁顿氨酸激酶 (BTK) 抑制剂的耐药性是常见的. 本综述探讨了BTK抑制剂耐药性机制和新疗法,包括BTK降解和下游信号抑制剂.

关键词:
布鲁顿氨酸激酶抑制剂 布鲁顿氨酸激酶抑制剂慢性淋巴细胞白血病 慢性淋巴细胞白血病阻力机制的阻力机制有针对性的治疗.

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