在评估肝硬化症使用超声波肝指数的反向散射异位素的效果
Jing Gao1, Ben Wilde1, Oliver D Kripfgans2
1Montana College of Osteopathic Medicine, Rocky Vista University, Billings, MT, USA.
概括
超声波肝指数 (HRI) 显示了评估肝脏脂肪的挑战. 尽管有理论上的补偿方法,脏皮层反向散射异质性可能会导致不准确的肝脂肪估计.
科学领域:
- 医疗成像医学成像
- 诊断性的超声波检查
- 肝病学 肝病学是一种肝病学.
背景情况:
- 肝硬化症的评估通常依赖于成像技术.
- 超声波肝指数 (HRI) 是一种用于估计肝脏脂肪含量的方法.
- 在HRI的准确和可靠应用方面存在挑战.
研究的目的:
- 为了评估肝脏肥胖症HRI的诊断性能.
- 识别和讨论与HRI测量相关的挑战.
- 将HRI与基于磁共振成像的质子密度脂肪分数 (MRI-PDFF) 进行比较.
主要方法:
- 在134名成年参与者中对HRI和MRI-PDFF进行了回顾性分析.
- 使用接收器操作特征曲线 (AUROC) 下面的区域评估HRI的诊断性能.
- 用回归图进行HRI计算的肝脏和脏采样地点的比较.
主要成果:
- 在8.2%的病例中,无法获得HRI测量.
- 在诊断肝硬化时,HRI显示AUROC为0.83.
- 皮皮质逆散异性导致位置依赖的HRI截止值,影响准确性.
结论:
- 肝脏肥胖症的HRI估计是基于超声波反向散射.
- 使用皮层反向散射的补偿方法在理论上是独立于位置的.
- 皮皮质逆向散射异质性损害了肝脂肪估计HRI的准确性.
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