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Frank L Dini¹, Valentina Barletta², Piercarlo Ballo³

¹Istituto Auxologico, IRCCS, Milan, Italy.

Echocardiography (Mount Kisco, N.Y.)

|February 20, 2025

概括

左心室外流速度时间积分 (LVOT-VTI) 是心力衰竭患者心血管死亡率的可重现和优异预测指标. 低于12.0厘米的LVOT-VTI表示最高风险,特别是当与低TAPSE/PASP相结合时.

科学领域:

心脏病学心脏病学
心声回声扫描 (Echocardiography) 是一种心声回声扫描.
心脏衰竭研究研究

背景情况:

左心室 (LV) 外流速度时间积分 (LVOT-VTI) 越来越多地用于心力衰竭 (HF) 患者分层.
常见的LV外流指数包括心脏指数 (CI) 和中风体积指数 (SVI).

研究的目的:

评估LVOT-VTI与CI和SVI相比的预后意义.
评估LVOT-VTI的可复制性和确定切割值.

主要方法:

多普勒心声扫描对424名患有LV系统功能障碍的HF门诊患者进行.
布兰德-阿尔特曼分析评估了指数可重复性.
考克斯回归和ROC分析评估了预后意义和切线值.
卡普兰-梅尔生存分析评估了综合的预后标志物.

主要成果:

在外流指数中,LVOT-VTI表现出最高的可重复性.
LVOT-VTI是最重要的心血管死亡的单变预测因子.
LVOT-VTI <12.0厘米是预测死亡率的最佳切断点 (ROC分析).
低的LVOT-VTI与降低的LV喷射率,升高的BNP和高的LV填充压力相关.
结合较低的LVOT-VTI和较低的TAPSE/PASP表示预后最差.

结论:

LVOT-VTI <12.0厘米是心血管结局的最佳预测因子,在心功能障碍的HF患者中.
LVOT-VTI是LV向前流的最可复制的指数.
将LVOT-VTI与TAPSE/PASP结合起来,可以确定生存率最低的患者.

关键词:

超声心电图 (Echocardiography) 是一种心声回声仪.心脏衰竭是因为心脏衰竭.预后预后预后

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