在患有慢性腰部疼痛的患者中,腰椎间盘和副脊柱肌肉变化的关联
Zhanglin Mou1, Wenfang Yi1, Mingbin Luo2
1The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Journal of back and musculoskeletal rehabilitation
|February 20, 2025
概括
慢性下背痛 (CLBP) 患者的腰椎间盘 (LDH) 与增加的副脊髓肌肉脂肪透相关,但不是横截面积 (CSA). 这一发现突显了脂肪变化,而不是LDH影响的肌肉的大小变化.
科学领域:
- 整形外科和运动医学
- 放射学和成像学 放射学和成像学
- 康复和物理治疗治疗.
背景情况:
- 慢性腰部疼痛 (CLBP) 与侧脊肌脂肪透和横截面区域 (CSA) 的改变有关.
- 腰椎间盘 (LDH) 与这些在CLBP患者的脊椎肌肉变化之间的特定关系需要进一步阐明.
研究的目的:
- 为了调查腰椎间盘 (LDH) 与脂肪透程度和CLBP患者中副脊椎肌肉中的CSA之间的关联.
主要方法:
- 494名CLBP患者的队列使用常规和IDEAL-IQ序列进行了MRI,以评估L4-S1级别的副脊髓肌肉质子密度脂肪分数 (PDFF) 和CSA.
- 腰椎间盘 (LDH) 在T2轴图像上进行评估,并使用视觉模拟尺度 (VAS) 测量疼痛强度.
- 肌肉CSA和PDFF通过高度平方进行标准化比较而正常化.
主要成果:
- 与没有LDH的患者相比,在L4/5时,患有LDH的患者在L4/5时表现出显著更高的副脊髓肌肉脂肪透 (PDFF) (p <0.05).
- 视觉模拟尺度 (VAS) 疼痛评分在LDH患者中显著升高 (p <0.05).
- 在有或没有LDH的CLBP患者之间没有观察到对脊柱肌CSA的显著差异.
结论:
- 腰椎间盘 (LDH) 在CLBP患者的特点是增加的副脊椎肌肉脂肪透,独立于肌肉横截面积 (CSA) 的变化.
- 特定类型或LDH的严重程度与脊肌脂肪透或CSA变化的程度没有相关性.
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