患有肺炎的婴儿的特征特征测试对特定免疫球蛋白E呈阳性
Li Hao1,2, Songqing Wang1,2, Wei Ji3
1Department of Pediatrics, Huaian Hospital of Huaian City, Huai'an, China.
概括
患有肺炎和牛奶过敏 (牛奶特异性免疫球蛋白E) 的婴儿可能需要更长的住院时间,特别是如果过敏仅对牛奶. 这凸显了儿童肺炎病例中需要仔细管理牛奶过敏的必要性.
科学领域:
- 儿科过敏和免疫学
- 呼吸系统医学 呼吸系统医学
- 传染性疾病 传染性疾病
背景情况:
- 肺炎是婴儿常见的呼吸道感染.
- 牛奶特异性免疫球蛋白E (sIgE) 表示对牛奶蛋白的过敏反应.
- 了解牛奶过敏和肺炎之间的相互作用对于有效的临床管理至关重要.
研究的目的:
- 分析患有肺炎的婴儿的临床特征,这些婴儿的乳特异性免疫球蛋白E (sIgE) 检测呈阳性.
- 为这组患者提供诊断,管理和预防参考资料.
- 为了比较纯牛奶sIgE,混合牛奶sIgE和没有过敏原sIgE的婴儿之间的临床特征.
主要方法:
- 对284名患有肺炎住院的婴儿进行了回顾性分析 (2017年1月 - 2020年12月).
- 患者被分为纯牛奶sIgE阳性,混合牛奶sIgE阳性和过敏原sIgE阴性组.
- 总体情况,临床特征,实验室测试,成像和病原体在不同组之间的比较.
主要成果:
- 16.20%的纯牛奶有SIGE,32.75%的混合牛奶有SIGE,51.06%的过敏原有SIGE阴性.
- 在一般情况,母乳养状态和呼吸道感染史中观察到显著差异.
- 纯牛奶和混合牛奶sIgE阳性组的住院时间较长,相比于负面组.
- 在混合牛奶SIGE组中,有更高的乙氨基酸细胞数量,在纯牛奶SIGE组中,有更高的*Haemophilus influenzae*发病率.
结论:
- 混合牛奶sIgE过敏原似乎不会使肺炎的婴儿的临床症状恶化.
- 只有牛奶sIgE阳性肺炎的婴儿需要更长时间的住院治疗.
- 对于患有牛奶过敏并出现肺炎的婴儿,需要给予更多的注意.
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