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Updated: May 27, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing

Published on: July 5, 2019

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融合基蛋白和合作突变在NUP98重新排列的白血病中定义疾病表型

Masayuki Umeda1, Ryan Hiltenbrand1, Nicole L Michmerhuizen1

  • 1Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.

medRxiv : the preprint server for health sciences
|February 20, 2025
PubMed
概括

患有NUP98重组的白血病表现出不同的细胞类型,这是由于合作突变影响分化. 这些发现揭示了NUP98重组型白血病中对脑膜抑制剂的阶段特异性耐药机制.

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