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Updated: Jun 29, 2026

Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique
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Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique

Published on: September 20, 2011

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使用分子印记聚合物的pH敏感纳米载体的设计和开发,以有针对性地输送型

Ayda Yari-Ilkhchi1,2,3, Abdolrahim Abbaszad Rafi4, Mehrdad Mahkam1

  • 1Faculty of Science, Chemistry Department, Azarbaijan Shahid Madani University Tabriz Iran mmahkam@yahoo.com mmahkam@gmail.com mahkam@azaruniv.ac.ir ayda.yari90@gmail.com.

Nanoscale advances
|February 20, 2025
PubMed
概括

磁性分子印记聚合物 (MMIPs) 选择性地捕获硫 (STL),为向药物输送提供了一个有希望的方法. 这些MMIP在特定的pH环境中表现出受控释放,增强了治疗潜力.

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Preparation of Neutrally-charged, pH-responsive Polymeric Nanoparticles for Cytosolic siRNA Delivery09:09

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Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
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Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...